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IFITS Research. The following data reflect the specifications of IFITS initiatives. For official Boise State University data, please consult the Office of Institutional Effectiveness (IE). IE's website.

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some members of the IFIT family have been solved to reveal an internal pocket for non-sequence-specific, but conformation- and modification-specific, nucleic acid binding. This review will focus on recent discoveries, which link IFITs to the anti-viral response, intrinsic to the innate immune system.

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Even though IFITs are renowned antiviral proteins, recent studies hint at their complex biological and molecular roles in cancer. In this review, we hypothesize that IFIT protein may serve as co-chaperones of Hsp90 ( Figure 4 ).

Type I/type III IFN and related factors regulate JEV infection and BBB ...

Interferon-induced proteins with tetratricopeptide repeats (IFITs) are highly expressed effectors of innate immunity that inhibit viral replication by incompletely understood mechanisms.

Interferon-Induced Genes of the Expanded IFIT Family Show ... - PLOS

The interferon-induced proteins with tetratricopeptide repeats (IFITs) are a family of antiviral proteins conserved throughout all vertebrates. IFIT1 binds tightly to non-self RNA, particularly capped transcripts lacking methylation on the first cap-proximal nucleotide, and inhibits their translatio ….