boi2 - Distinct roles of the polarity factors Boi1 and Boi2 in the control of ... cv777

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We identify 2 critical aromatic residues, present in both Boi1 and Boi2, in the essential C-terminal Pleckstrin-Homology domain, that cause temperature-sensitive growth resulting in defects in polarized growth leading to cell lysis.

Generation and characterization of conditional yeast mutants affecting ...

GAL1 promoter-driven overexpression of MSB1 in yeast cells caused bud elongation and the formation of multiple buds (see next section). We found that GAL1 -driven overexpression of MSB1 also produced elongated buds in boi1 Δ and boi2 Δ cells but not in boi1 Δ boi2 Δ cells ( Fig. 3A ).

Distinct roles of the polarity factors Boi1 and Boi2 in the control of ...

The Boi1 protein and its functionally redundant homolog Boi2 p have been implicated in actin cytoskeleton reorganization and establishment of cell polarity (2, 1). boi1 boi2 double mutant cells become large and round or lyse with buds, displaying defects in bud formation and in the maintenance of cell polarity (1).

BOI2 | SGD - Saccharomyces Genome Database

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Msb1 Interacts with Cdc42, Boi1, and Boi2 and May Coordinate Cdc42 and ...

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